Intraocular retinal prosthesis
The question of how intraocular retinal prostheses independently activated micro-electrodes in an array it will take to make useful visual functional improvement is ever present. In the first setup, charge-balanced pulses were delivered to the retinal surface via electrodes inserted through an open sky approach in normal or blind retinal degenerate rd mice.
Delineating the optimum parameters will decrease the current requirements. In both of these tasks, subjects were significantly better in their performance with the device turned on versus turned off.
External hardware will capture images, process them, and generate instructions which will then be transmitted to implanted circuitry via a telemetry link.
This high-acuity implant will be inserted epiretinally. Development of electrode device ongoing with plans to enter human clinical trials upon completion. The implants were successful in producing evoked cortical potentials in half of the animals tested. Morphometric analysis of the extramacular retina from postmortem eyes with retinitis pigmentosa.
At 14 months post implantation, the implant and retina surrounding it were examined and there formula to photosynthesis no noticeable changes to anatomical integrity. And, since most affected individuals suffer from progressive diseases, long-term viability of retinal interfaces is uncertain.
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